howard male wrote: . . . 'hundreds of typos.' This can't help but imply a laziness and carelessness on my part, but the fact of the matter is that I must have been through that manuscript half a dozen times tightening up the prose and making all sorts of little changes, but for some reason my eyes have obviously become blind to certain kinds of typos, and even if I went through it again, now, with this knowledge, I'm fairly certain I'd still manage to miss 70% of them. Luckily my sister is now reading the book and is marking these mistakes, so future copies won't be quite so blighted.
It is very hard to edit and proofread your own material. It's not lazyness or carelessness. After awhile, your eyes and brain will just glaze over. Don't beat yourself up over it. Besides, some people are good at one thing and some at another. Proofing and editing are actually pretty specialized skills, although many people think they can do them.
If your sister is Word-literate, it might be worth her marking things up in the Word doc using the "Track Changes" function. Actually, anybody who's reading it from the screen could mark it up for you and send it back â€” if they were willing to perform the service and you were prepared for the onslaught. Sorry, but I personally did not think the manuscript was ready to be sent to a publisher in today's publishing business because of the typos.